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Antibody Masterclasses

Andrew Bradbury has been giving an annual “Introduction to antibody engineering” course at PepTalk with Prof. Jim Marks for a number of years. In 2023 he gave the course alone and had it filmed. Annual updates tend to be relatively minor. The eight videos, totaling ~6 hours, cover the subjects below.

1. Introduction, market, antibody basics, structure, genetics, and the generation of diversity

2. Antibody Humanization

3. Making Antibody Libraries

4. Phage Display

5. Yeast, mammalian, bacterial and in vitro display

6. Next generation sequencing in antibody discovery

7. Antibody affinity maturation and developability optimization

8. Antibody characterization and developability