When we undertake an antibody discovery campaign for you, our goal is to generate as many different target-specific antibodies fulfilling your requirements as possible.
Using three powerful coordinating technologies, we first carry out selections from our Generation 3 phage display libraries to obtain an initial pool of antibody leads with maximum diversity. We then use yeast display to narrow this down to a diverse, high affinity fully binding population, reflecting requirements for cross-reactivity, ligand antagonism or additional specificity needs. Finally, we evaluate selection outputs with next generation sequencing and AbXtract, Specifica’s NGS analysis software.