We use next generation sequencing throughout library construction and downstream selection output analyses. This allows us to directly measure the diversity of each exclusive library we build, to ensure it reaches our high standards.
Next Generation Sequencing (NGS)
By applying NGS and our in-house bioinformatic and artificial intelligence (AI) platform to selection outputs, we are usually able to identify five hundred to five thousand different clonotypes. Once representative clonotype sequences have been identified, Specifica has developed a number of different methods to go “from sequence to clone” that can be used to access the most promising leads.